How Does Fisetin Helps Affected Glial Cells?

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Phyllis Cort Asked by Phyllis Cort 1 month, 1 week ago
Gardenality Seed · Zone 8A · 10° to 15° F

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Answer #1 · Darlene Yates's Answer · CAD-31 has potent neuroprotective properties in six distinct nerve cell assays that mimic toxicities observed in the old brain. Pharmacological and preliminary toxicological studies show that CAD-31 is brain-penetrant and likely safe. When fed to old, symptomatic APPswe/PS1?E9 AD mice starting at 10 months of age for 3 additional months in a therapeutic model of the disease, there was a reduction in the memory deficit and brain inflammation, as well as an increase in the expression of synaptic proteins. Small-molecule metabolic data from the brain and plasma showed that the major effect of CAD-31 is centered on fatty acid metabolism and inflammation. Pathway analysis of gene expression data showed that https://www.wisepowder.com/product-details/cad-31/ had major effects on synapse formation and AD energy metabolic pathways.)

Darlene Yates Answered by Darlene Yates 1 month, 1 week ago
Gardenality Seed · Zone 8A · 10° to 15° F


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